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Sterile micronization is desired to avoid terminal sterilization.
Small scale fluid jet micronizers can be enclosed inside a compact isolator and sterilized with one of the following techniques:
 Sterilization with vaporized H2O2 for isolator and to fluid jet mill only if applicable
Steam sterilization for fluid jet mill or autoclave and sterile transfer
Production fluid jet micronizers need of wider sterile area and are sterilized with one of the following techniques:
Sterile in Place Processing (SIP) with fluent steam
SIP based on pressurized steam at 121°C and temperature mapping
SIP with hydrogen peroxide solution if applicable
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receive an engineered solution to your micronization process
application.
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